Biomaterial Database

[Toxicology of metals and biocompatibility of metallic implant materials]. 1984

M Ungethüm, and W Winkler-Gniewek

Based on general toxicological knowledge and the notorious measurements of corrosion parameters this paper is an attempt to define the biocompatibility of metallic materials used for implantation in the human body. Mentioned are essentially those implant materials and its metallic elements which are subjectmatter of a standard specification. The previous experiences concerning "metal allergy" are shortly recapitulated. Model conceptions about the mechanisms of tissue reaction to metallic elements are indicated.

UI	MeSH Term	Description	Entries
D008670	Metals	Electropositive chemical elements characterized by ductility, malleability, luster, and conductance of heat and electricity. They can replace the hydrogen of an acid and form bases with hydroxyl radicals. (Grant & Hackh's Chemical Dictionary, 5th ed)	Metal
D003343	Corrosion	The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Corrosions
D005549	Foreign-Body Reaction	Chronic inflammation and granuloma formation around irritating foreign bodies.	Foreign Body Reaction,Reaction, Foreign-Body
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001672	Biocompatible Materials	Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.	Biomaterials,Bioartificial Materials,Hemocompatible Materials,Bioartificial Material,Biocompatible Material,Biomaterial,Hemocompatible Material,Material, Bioartificial,Material, Biocompatible,Material, Hemocompatible
D012995	Solubility	The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Solubilities
D019736	Prostheses and Implants	Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.	Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic