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To simplify the diagnosis of chlamydial genital infection, we used a fluorescein-conjugated monoclonal antibody in immunofluorescence tests on smears prepared from urethral or cervical secretions obtained directly from patients. This direct test, requiring less than 30 minutes to perform, was based on the detection of extracellular chlamydial elementary bodies. A comparison of the direct test with cultures stained with iodine on specimens from 926 patients demonstrated a sensitivity of 93 per cent and a specificity of 96 per cent. The direct test provides a rapid, simple, and sensitive method for the diagnosis of chlamydial infection, which can be performed in laboratories that do not have tissue-culture capability.
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
March 1986,
Nederlands tijdschrift voor geneeskunde,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
September 1985,
Nederlands tijdschrift voor geneeskunde,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
August 1985,
Revista medica de Chile,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
November 1985,
Infection and immunity,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
October 1985,
The Journal of infectious diseases,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
November 1987,
Nippon Ganka Gakkai zasshi,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
July 1984,
Lancet (London, England),
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
May 1984,
Lancet (London, England),
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
June 1986,
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete,
M R Tam, and
W E Stamm, and
H H Handsfield, and
R Stephens, and
C C Kuo, and
K K Holmes, and
K Ditzenberger, and
M Krieger, and
R C Nowinski
January 1991,
Zentralblatt fur Gynakologie,
