-transparent.png){kind=logo}
The degree of fluorescence polarization (P value) of 1,6-diphenyl-1,3,5-hexatriene has been shown to be an excellent indicator of the lecithin/sphingomyelin (L/S) ratio in laboratory prepared liposomal dispersions. In order to test the validity of this technique in amniotic fluid, the L/S ratio and P value of 161 amniotic fluid specimens were determined. In 127 the P value was less than or equal to 0.336 and the L/S ratio was greater than or equal to 2. In 26 the P value was greater than 0.336 and the L/S ratio was less than 2 (P less than 0.05). The amniotic fluid P value is affected by blood or meconium but not by surgical lubricants or bilirubin. We concluded that the degree of fluorescence polarization of amniotic fluid indicates fetal lung maturity as reliably as the L/S ratio. However, this method has important technical and practical advantages that make it more applicable for a clinical laboratory.
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
August 1986,
Obstetrics and gynecology,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
July 1979,
Archives of gynecology,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
January 1993,
Journal of perinatal medicine,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
August 2003,
Photochemistry and photobiology,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
June 1986,
Clinical chemistry,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
April 1987,
American journal of perinatology,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
March 1982,
Clinical chemistry,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
March 1981,
Obstetrics and gynecology,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
August 1983,
Clinical chemistry,
T A Blumenfeld, and
R I Stark, and
L S James, and
J D George, and
I Dyrenfurth, and
V J Freda, and
M Shinitzky
March 1985,
Obstetrics and gynecology,
