[Pathological anatomy and pathogenesis of experimental pancreatitis]. 1984

A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian

The necrotic and inflammatory processes in the albino rats pancreas were studied by histological, immunomorphological and electron microscopic techniques after freezing of the pancreas. Early morphological sings of acinar cells destruction were revealed. The mechanism of secret "leakage" from zimogen granules into acinar cell cytoplasm was shown. The stages of pathologic process corresponding to different types of pancreatitis were established. The inflammatory reaction formed in the stage of parenchymal necrosis was characterised by an early activation of fibroblastic and macrophagal cells and by the delay of necrotic tissue elimination with their following calcification. The chronic pancreatitis developed on the immune basis in the intact parts of the pancreas.

UI MeSH Term Description Entries
D008297 Male Males
D008833 Microcirculation The circulation of the BLOOD through the MICROVASCULAR NETWORK. Microvascular Blood Flow,Microvascular Circulation,Blood Flow, Microvascular,Circulation, Microvascular,Flow, Microvascular Blood,Microvascular Blood Flows,Microvascular Circulations
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D009336 Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D010179 Pancreas A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
D010195 Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. Acute Edematous Pancreatitis,Acute Pancreatitis,Pancreatic Parenchyma with Edema,Pancreatic Parenchymal Edema,Pancreatitis, Acute,Pancreatitis, Acute Edematous,Peripancreatic Fat Necrosis,Acute Edematous Pancreatitides,Acute Pancreatitides,Edema, Pancreatic Parenchymal,Edematous Pancreatitides, Acute,Edematous Pancreatitis, Acute,Fat Necrosis, Peripancreatic,Necrosis, Peripancreatic Fat,Pancreatic Parenchymal Edemas,Pancreatitides, Acute,Pancreatitides, Acute Edematous,Parenchymal Edema, Pancreatic,Peripancreatic Fat Necroses
D003080 Cold Temperature An absence of warmth or heat or a temperature notably below an accustomed norm. Cold,Cold Temperatures,Temperature, Cold,Temperatures, Cold
D004487 Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. Dropsy,Hydrops,Anasarca
D006471 Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D006652 Histological Techniques Methods of preparing tissue for examination and study of the origin, structure, function, or pathology. Histologic Technic,Histologic Technics,Histologic Technique,Histologic Techniques,Histological Technics,Technic, Histologic,Technics, Histologic,Technique, Histologic,Techniques, Histologic,Histological Technic,Histological Technique,Technic, Histological,Technics, Histological,Technique, Histological,Techniques, Histological

Related Publications

A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
May 1981, World journal of surgery,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
August 1990, Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1959, Arkhiv patologii,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1965, Arkhiv patologii,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1972, Bulletin et memoires de la Societe des chirurgiens de Paris,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
June 1973, Hippokrates,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1976, Minerva gastroenterologica,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1961, Ceskoslovenska oftalmologie,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
May 1950, Schweizerische medizinische Wochenschrift,
A S Kanaian, and N K Permiakov, and G P Titova, and K P Arabadzhian
January 1977, Arkhiv patologii,
Copied contents to your clipboard!