Effect of intravenous insulin infusion on mortality among diabetic patients after myocardial infarction. 1984

D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost

A review of the records of 353 diabetic patients after a myocardial infarction confirmed the high mortality associated with the condition. The influence of improved diabetic control achieved by intravenous insulin was assessed in 64 patients and compared with earlier experience in a diabetic control group. The frequency of the major complications of myocardial infarction was unchanged and the death rate in both groups was identical (33%); even the patients with blood glucose concentrations greater than 20 mmol/l on admission failed to benefit. Thus careful control of blood glucose concentrations after myocardial infarction in diabetic patients fails to improve the outcome of this high risk group.

UI MeSH Term Description Entries
D007263 Infusions, Parenteral The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping. Intra-Abdominal Infusions,Intraperitoneal Infusions,Parenteral Infusions,Peritoneal Infusions,Infusion, Intra-Abdominal,Infusion, Intraperitoneal,Infusion, Parenteral,Infusion, Peritoneal,Infusions, Intra-Abdominal,Infusions, Intraperitoneal,Infusions, Peritoneal,Intra Abdominal Infusions,Intra-Abdominal Infusion,Intraperitoneal Infusion,Parenteral Infusion,Peritoneal Infusion
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D003920 Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
September 1996, BMJ (Clinical research ed.),
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
January 2006, Seminars in thoracic and cardiovascular surgery,
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
September 1985, British medical journal (Clinical research ed.),
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
August 1985, British medical journal (Clinical research ed.),
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
August 1986, International journal of cardiology,
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
February 1984, The New England journal of medicine,
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
February 1998, Circulation,
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
January 1997, Journal of diabetes and its complications,
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
January 1997, BMJ (Clinical research ed.),
D J Gwilt, and M Petri, and P Lamb, and M Nattrass, and B L Pentecost
January 2004, Zeitschrift fur Kardiologie,
Copied contents to your clipboard!