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Ovarian function was assessed in 24 women after renal transplantation who were treated either with cyclosporin A (10 patients) or with a combination of azathioprine and prednisone (14 patients) as immunosuppressive therapy. The different regimens were not associated with any differences in clinical or endocrine indices of ovarian function (LH, FSH, prolactin, testosterone, oestradiol, dehydroepiandrosterone sulphate). Excessive hair growth was common in both treatment groups. Levels of testosterone and dehydroepiandrosterone were higher in cyclosporin-treated women but this was due to prednisone-induced suppression of adrenal androgen output in the azathioprine- and prednisone-treated women. Excessive hair growth was present in postmenopausal women on both treatments suggesting that hypertrichosis is a consequence of renal transplantation and is not a specific side-effect of cyclosporin A therapy.
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
February 1989,
Polskie Archiwum Medycyny Wewnetrznej,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
February 1986,
Presse medicale (Paris, France : 1983),
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
February 1985,
The Medical journal of Australia,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
March 1990,
Archives of disease in childhood,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
January 1988,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
July 1992,
Polskie Archiwum Medycyny Wewnetrznej,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
December 1985,
Presse medicale (Paris, France : 1983),
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
January 1990,
International urology and nephrology,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
February 1989,
Transplantation proceedings,
D J Handelsman, and
I F McDowell, and
I D Caterson, and
D J Tiller, and
B M Hall, and
J R Turtle
January 1992,
Acta haematologica Polonica,
