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We treated a man who developed endopthalmitis six weeks after a seemingly minor injury. Cultures were positive for Propionibacterium acnes, an anerobic, Gram-positive rod that is a normal inhabitant of the conjunctiva but is rarely a cause of endophthalmitis. The patient underwent vitrectomy and lensectomy with intravitreal injection of antibiotics followed by systemic cephalothin and prednisone. Clinical and visual improvement was rapid.
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