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We report here the results obtained with a new test of prolactin (PRL) release in six normal pre-pubertal boys, eleven children with short stature of non-pituitary origin and in thirteen pituitary dwarfs. The test consists of the administration of 100 mg of sulpiride i.m. and the measurement of PRL in serum samples up to 120 min after injection. Baseline PRL concentrations were not clearly different in the three groups. After sulpiride a marked increase (3--10 times over control values) in PRL was noted in all normal and short children without pituitary disease. A complete failure of response was observed in ten of the thirteen pituitary dwarfs. It is concluded that sulpiride has considerable potential in the differential diagnosis of children with stunted growth.
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
January 1980,
Endokrynologia Polska,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
June 1975,
Bollettino della Societa italiana di biologia sperimentale,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
July 1978,
Fertility and sterility,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
February 1974,
Nihon Naibunpi Gakkai zasshi,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
May 1974,
Minerva pediatrica,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
October 1976,
Bollettino della Societa italiana di biologia sperimentale,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
November 1981,
Acta endocrinologica,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
January 1992,
Journal de gynecologie, obstetrique et biologie de la reproduction,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
November 1974,
Helvetica paediatrica acta,
M L Batrinos, and
S N Pavlou, and
S A Pitoulis, and
A P Sfikaki, and
C Anousakis, and
T K Alexandrides, and
G P Piaditis
November 1974,
Experientia,
