Biomaterial Database

Ciramadol, a new potent analgesic, used intravenously in renal colic. 1984

W Oosterlinck, and H Minnaert, and A Verbaeys

In an open investigation, ciramadol, a partial agonist of opioid, was found to be a potent analgesic when 20 mg was given intravenously to 30 patients experiencing severe pain of renal colic. Total pain relief was obtained in 9 patients, while very good pain relief was obtained in 17 others. However, severe pain was experienced again in 7 of them after 1 to 2 hours. Vomiting and nausea occurred in 9 patients, and dizziness was present in 7 patients. The haemodynamic equilibrium was not changed by the analgesic.

UI	MeSH Term	Description	Entries
D007275	Injections, Intravenous	Injections made into a vein for therapeutic or experimental purposes.	Intravenous Injections,Injection, Intravenous,Intravenous Injection
D007674	Kidney Diseases	Pathological processes of the KIDNEY or its component tissues.	Disease, Kidney,Diseases, Kidney,Kidney Disease
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D003085	Colic	A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.	Abdominal Cramps,Infantile Colic,Abdominal Cramp,Colic, Infantile,Cramp, Abdominal,Cramps, Abdominal
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000588	Amines	A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)	Amine