Biomaterial Database

Ocular manifestation of polychlorinated biphenyl (PCB) intoxication. Its relationship to PCB blood concentration. 1983

Y A Fu

One hundred seventeen patients had polychlorinated biphenyl (PCB) poisoning. Thirty-nine patients were male; 78 were female. The primary ocular manifestations were profuse discharge from the eyes (80.5%), swelling and pigmentation of the upper lids (58.9%), abnormal pigmentation of conjunctivae (66.6%), and hypersecretion and swelling of the meibomian glands (70.1%). The severity of these changes were directly related to the PCB concentration in the blood. Particularly, heavy pigmentation of conjunctivae, abnormal cystic formation, and hypersecretion of the meibomian glands occurred in those patients whose blood PCB concentration was greater than 41 parts per billion. Ocular signs not only provide early signs for diagnosis, but also serve to indicate the severity of PCB poisoning.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008537	Meibomian Glands	The sebaceous glands situated on the inner surface of the eyelids between the tarsal plates and CONJUNCTIVA.	Glandulae Tarsales,Tarsal Glands,Gland, Meibomian,Gland, Tarsal,Meibomian Gland,Tarsal Gland
D010859	Pigmentation Disorders	Diseases affecting PIGMENTATION, including SKIN PIGMENTATION.	Incontinentia Pigmenti Achromians,Ito Syndrome,Schamberg's Disease,Schamberg Disease,Disease, Schamberg,Disease, Schamberg's,Disorder, Pigmentation,Disorders, Pigmentation,Pigmentation Disorder,Schambergs Disease,Syndrome, Ito
D011078	Polychlorinated Biphenyls	Industrial products consisting of a mixture of chlorinated biphenyl congeners and isomers. These compounds are highly lipophilic and tend to accumulate in fat stores of animals. Many of these compounds are considered toxic and potential environmental pollutants.	PCBs,Polychlorinated Biphenyl,Polychlorobiphenyl Compounds,Biphenyl, Polychlorinated,Biphenyls, Polychlorinated,Compounds, Polychlorobiphenyl
D003229	Conjunctival Diseases	Diseases involving the CONJUNCTIVA.	Conjunctival Disease,Disease, Conjunctival,Diseases, Conjunctival
D004487	Edema	Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	Dropsy,Hydrops,Anasarca
D005128	Eye Diseases	Diseases affecting the eye.	Eye Disorders,Eye Disease,Eye Disorder
D005141	Eyelid Diseases	Diseases involving the EYELIDS.	Disease, Eyelid,Diseases, Eyelid,Eyelid Disease
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man