Results of 141 therapeutic abortions in the second trimestre of pregnancy with Prostaglandine E2 gel or Prostaglandine F2 alpha gel are reported. Some required oxytocin augmentation. There were 102 legal abortions. Five cases had medical indications, 97 cases had psychosocial indications. There were 39 cases of missed abortion or intra-uterine fetal death. Prostaglandine gel was developed in 1973 by Lippert. The Prostaglandine gel was administered by catheter into the extra-amniotic space. Of all 141 cases 136 (96.5%) aborted within 36 hours. The mean administration-abortion interval was 10 h 5 min-3 h 45 min in the group with Prostaglandine E2 gel and 10 h 4 min +/- 6 h 3 min in the group with Prostaglandine E2 gel augmented with Oxytocin. In the group with Prostaglandine F2 alpha gel the mean interval was 9 h 52 min +/- 6 h 50 min and in the group with Prostaglandine F2 alpha gel augmented with oxytocin the mean interval was 16 h 17 min +/- 8 h 19 min. The mean dosage of Prostaglandine corresponded to the mean administration abortion interval time. 1/3 of the cases had side effects. The method and it's result are compared with other series.