Parenteral nutrition in cancer therapy: a useful adjunct? 1983

J A Darbinian, and A M Coulston

The value of nutritional support during cancer therapy continues to be debated. Data from studies concerned with nutritional rehabilitation of malnourished cancer patients suggest that in certain patient subgroups, total parenteral nutrition may improve tolerance to and increase efficacy of anti-neoplastic treatment modalities. In contrast, other investigators have questioned whether nutritional support of cancer patients may actually benefit the tumor at the expense of the host. Animal tumor model studies indicate that further research is warranted to ascertain whether human host and tumor tissue differentially utilize nutrient substrates and whether these differences may be used to the advantage of the host.

UI MeSH Term Description Entries
D007121 Immunocompetence The ability of lymphoid cells to mount a humoral or cellular immune response when challenged by antigen. Competence, Immunologic,Immunologic Competence,Immunological Competence,Competence, Immunological
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D010288 Parenteral Nutrition The administering of nutrients for assimilation and utilization by a patient who cannot maintain adequate nutrition by enteral feeding alone. Nutrients are administered by a route other than the alimentary canal (e.g., intravenously, subcutaneously). Intravenous Feeding,Nutrition, Parenteral,Parenteral Feeding,Feeding, Intravenous,Feeding, Parenteral,Feedings, Intravenous,Feedings, Parenteral,Intravenous Feedings,Parenteral Feedings
D011502 Protein-Energy Malnutrition The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses. Marasmus,Protein-Calorie Malnutrition,Malnutrition, Protein-Calorie,Malnutrition, Protein-Energy,Malnutritions, Protein-Energy,Protein Calorie Malnutrition,Protein Energy Malnutrition
D011878 Radiotherapy The use of IONIZING RADIATION to treat malignant NEOPLASMS and some benign conditions. Radiotherapy, Targeted,Targeted Radiotherapy,Radiation Therapy,Radiation Therapy, Targeted,Radiation Treatment,Targeted Radiation Therapy,Radiation Therapies,Radiation Therapies, Targeted,Radiation Treatments,Radiotherapies,Radiotherapies, Targeted,Targeted Radiation Therapies,Targeted Radiotherapies,Therapies, Radiation,Therapies, Targeted Radiation,Therapy, Radiation,Therapy, Targeted Radiation,Treatment, Radiation
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013514 Surgical Procedures, Operative Operations carried out for the correction of deformities and defects, repair of injuries, and diagnosis and cure of certain diseases. (Taber, 18th ed.). Surgical Procedures,Ghost Surgery,Operative Procedures,Operative Surgical Procedure,Operative Surgical Procedures,Procedure, Operative Surgical,Procedures, Operative Surgical,Surgery, Ghost,Surgical Procedure, Operative,Operative Procedure,Procedure, Operative,Procedure, Surgical,Procedures, Operative,Procedures, Surgical,Surgical Procedure
D064420 Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. Drug-Related Side Effects and Adverse Reaction,Adverse Drug Event,Adverse Drug Reaction,Drug Side Effects,Drug Toxicity,Side Effects of Drugs,Toxicity, Drug,Adverse Drug Events,Adverse Drug Reactions,Drug Event, Adverse,Drug Events, Adverse,Drug Reaction, Adverse,Drug Reactions, Adverse,Drug Related Side Effects and Adverse Reaction,Drug Related Side Effects and Adverse Reactions,Drug Side Effect,Drug Toxicities,Effects, Drug Side,Reactions, Adverse Drug,Side Effect, Drug,Side Effects, Drug,Toxicities, Drug

Related Publications

J A Darbinian, and A M Coulston
February 1996, Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition,
J A Darbinian, and A M Coulston
February 1971, The Surgical clinics of North America,
J A Darbinian, and A M Coulston
January 1979, Rinsho hoshasen. Clinical radiography,
J A Darbinian, and A M Coulston
October 1996, The Journal of urology,
J A Darbinian, and A M Coulston
February 1993, The American journal of gastroenterology,
J A Darbinian, and A M Coulston
November 1985, Nederlands tijdschrift voor geneeskunde,
J A Darbinian, and A M Coulston
January 1981, Cancer treatment reports,
J A Darbinian, and A M Coulston
September 1994, American journal of hospital pharmacy,
J A Darbinian, and A M Coulston
April 2014, Nature reviews. Clinical oncology,
J A Darbinian, and A M Coulston
January 2000, Diabetic medicine : a journal of the British Diabetic Association,
Copied contents to your clipboard!