-transparent.png){kind=logo}
The mutagenic activities of N-nitrosobis(2-hydroxypropyl)amine (BHP) and its related compounds were studied in Salmonella typhimurium TA100 and TA98 strains by Ames's liquid incubation assay in the presence or absence of lung and liver S9 of rats treated with polychlorinated biphenyl (PCB). BHP and its related compounds, N-nitroso-(2-hydroxypropyl)(2-oxopropyl)amine (HPOP), N-nitrosobis(2-oxopropyl)amine (BOP), N-nitrosobis(2-acetoxypropyl)amine (BAP), and N-nitroso-2,6-dimethylmorpholine (NDMM) showed negative mutagenicity in the absence of lung and liver S9 in TA100 and TA98 strains while those compounds showed positive in the presence of liver S9 in TA100 strain. HPOP and BOP showed positive mutagenic activity in the presence of lung S9 in TA100 strain. HPOP showed the strongest mutagenic activity in the presence of lung and liver S9.
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
January 1987,
IARC scientific publications,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
June 1989,
Cancer letters,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
July 1979,
Journal of the National Cancer Institute,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
January 1983,
Carcinogenesis,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
March 1984,
Journal of the National Cancer Institute,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
February 1992,
Carcinogenesis,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
February 2000,
Cancer letters,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
September 1977,
Cancer letters,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
December 1978,
Cancer letters,
Y Mori, and
T Niwa, and
H Takahashi, and
K Toyoshi, and
A Denda, and
S Takahashi, and
Y Konishi
January 1984,
IARC scientific publications,
