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Thirty patients with chronic renal failure on maintenance hemodialysis (HD) were studied. Plasma chemotactic activity was estimated using the "under agarose" chemotaxis assay during the first 2 h of HD. It was found that in the fifth minute of HD, patients' plasma became chemotactic, reaching the maximum activity at the tenth minute. The chemotactic activity appearance correlated significantly with the decline in the number of the peripheral neutrophils. Patients' neutrophils, after a single passage through the cellophane coil of the dialyzer, revealed significant impairment of directed migration toward both complementary and bacterial chemoattractants. Moreover, the chemotactic properties of neutrophils obtained from dialyzed patients before HD were significantly lower than had been estimated in 15 nondialyzed patients with chronic renal failure. The results confirm HD-induced complement activation and might explain the mechanisms of the increased susceptibility of dialyzed patients to bacterial infections.
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
July 1990,
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
January 1978,
Acta medica Scandinavica,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
December 1976,
The Journal of laboratory and clinical medicine,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
August 2000,
International journal of cardiology,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
January 1989,
International journal of tissue reactions,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
August 2007,
Infection and immunity,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
July 1973,
Infection and immunity,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
May 1992,
Photochemistry and photobiology,
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
January 1984,
Science (New York, N.Y.),
B Wierusz-Wysocka, and
H Wysocki, and
R Czarnecki, and
H Siekierka, and
K Baczyk, and
K Wysocki
January 1985,
International journal of tissue reactions,
