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Spin echo Fourier transform proton n.m.r. spectra of whole blood contain resonances from both erythrocytes and plasma. A large number of well-resolved signals from mobile protons of low-molecular-weight metabolites in plasma and serum have been identified. Spectra from the plasmas of eight animal species and commercial, quality control sera are compared. CaEDTA2- and MgEDTA2- resonances can be used for the simultaneous determination of EDTA-chelatable calcium and magnesium concentrations in intact plasma and other biological fluids. Cholesterol is too immobile to contribute to the spectra of intact plasma, but is readily estimated by n.m.r. in both its free and esterified forms after extraction into methanol.
J K Nicholson, and
M J Buckingham, and
P J Sadler
February 1986,
International journal of peptide and protein research,
J K Nicholson, and
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July 1995,
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J K Nicholson, and
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P J Sadler
July 1994,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
December 1982,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
September 1983,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
November 1989,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
January 1983,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
August 1984,
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J K Nicholson, and
M J Buckingham, and
P J Sadler
August 1986,
International journal of peptide and protein research,
J K Nicholson, and
M J Buckingham, and
P J Sadler
June 1986,
The Biochemical journal,
