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A radial immunodiffusion assay for tear lactoferrin is described. Tear samples, collected on filter paper discs, could be applied directly to immunodiffusion plates after blotting. In 58 tear samples from healthy subjects an average lactoferrin concentration of 1.42 g/l was found. A high degree of correlation was found between the lactoferrin radial immunodiffusion and the lysozyme agar diffusion assay in a heterogeneous group, ranging from healthy subjects to patients with severe keratoconjunctivitis sicca. A lower limit of normal (0.78 g/l) could be determined for the tear lactoferrin concentration. The assay does not require laboratory facilities and therefore is an easily accessible alternative for or an addition to lacrimal gland function tests currently used.
P T Janssen, and
O P van Bijsterveld
January 1982,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
P T Janssen, and
O P van Bijsterveld
July 1998,
Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere,
P T Janssen, and
O P van Bijsterveld
January 1970,
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology,
P T Janssen, and
O P van Bijsterveld
November 1986,
Clinical chemistry,
P T Janssen, and
O P van Bijsterveld
April 1978,
Immunochemistry,
P T Janssen, and
O P van Bijsterveld
January 1980,
Proceedings, annual meeting of the United States Animal Health Association,
P T Janssen, and
O P van Bijsterveld
July 1978,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
P T Janssen, and
O P van Bijsterveld
April 1983,
Journal of immunological methods,
P T Janssen, and
O P van Bijsterveld
April 1972,
Acta medicinae Okayama,
P T Janssen, and
O P van Bijsterveld
March 1980,
Ceskoslovenska epidemiologie, mikrobiologie, imunologie,
