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The growth hormone responses to arginine infusion and to insulin-induced hypoglycemia were studied in 13 patients with neoplastic disease after treatment with radiation and chemotherapy. Patients who received intensive cranial radiation (greater than 2,400 rads) had no response to either arginine or insulin; those who received moderate cranial radiation (greater than or equal to 2,400 rads) had GH response to arginine but not to insulin; patients receiving no cranial radiation responded to both arginine and insulin. These data support the hypothesis that GH secretion in response to arginine infusion has a different mechanism in contrast to the response to insulin-induced hypoglycemia and that the latter is more vulnerable to cranial radiation.
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
May 1992,
Clinical endocrinology,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
January 1973,
Dermatologica,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
January 1985,
Hormone research,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
March 1978,
Diabete & metabolisme,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
January 1979,
Nephron,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
July 1975,
The Journal of clinical endocrinology and metabolism,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
December 1971,
The Journal of endocrinology,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
June 1969,
Pediatrics,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
February 1969,
The Journal of pediatrics,
W P Dickinson, and
D H Berry, and
L Dickinson, and
M Irvin, and
H Schedewie, and
R H Fiser, and
M J Elders
December 1967,
Lancet (London, England),
