Modified NF method for quantitative determination of pentaerythritol tetranitrate. 1978

V D Gupta

A modified NF method for the quantitative determination of pentaerythritol tetranitrate is reported. A solution of powder is made directly from the dosage form in glacial acetic acid and is then reacted with phenoldisulfonic acid TS. The proposed method saves approximately 75% of the time required with the NF method. The results on six differnet commercial dosage forms with four different colors and three other active ingredients are reported.

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D010417 Pentaerythritol Tetranitrate A vasodilator with general properties similar to NITROGLYCERIN but with a more prolonged duration of action. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1025) Dilcoran,Erinit,Nirason,Nitrodex,Pentalog,Peritrate,Tetrate,Tetranitrate, Pentaerythritol
D010602 Pharmacopoeias as Topic Works about authoritative treatises on drugs and preparations, their description, formulation, analytic composition, physical constants, main chemical properties used in identification, standards for strength, purity, and dosage, chemical tests for determining identity and purity, etc. Formulary, National,National Formulary,Formularies, National,National Formularies
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.

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