-transparent.png){kind=logo}
To determine whether or not disodium cromoglycate (DSCG) inhibits the bronchoconstriction induced by inhalation of kerosene aerosol in rabbits, we carried out a study in 31 normal rabbits which were divided into four groups. DSCG was administered through the tracheal cannula twenty minutes before exposure to kerosene aerosol. Twenty and forty milligrams of DSCG as total doses inhibited kerosene induced bronchoconstriction in large airways (RL), but 5 mg of drug did not have any effect. DSCG at any tested dose did not inhibit the decreased dynamic lung compliance (CL) which was observed after kerosene aerosol. Our findings suggest that DSCG at high dose inhibit the bronchoconstrictor effect of kerosene in large airways of rabbits.
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
February 1989,
The American review of respiratory disease,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
October 1983,
British journal of diseases of the chest,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
September 1981,
The American review of respiratory disease,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
January 1982,
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
September 1972,
British journal of pharmacology,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
January 1981,
British medical journal (Clinical research ed.),
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
January 1982,
Zeitschrift fur Erkrankungen der Atmungsorgane,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
July 1985,
British journal of clinical pharmacology,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
January 1985,
Contact dermatitis,
A Casacó, and
L Arruzazabala, and
R González, and
A Rodríguez de la Vega
May 2001,
Immunopharmacology and immunotoxicology,
