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We studied the effects of dobutamine on blood gases, venous admixture and hemodynamics in ten patients suffering an acute myocardial infarction (AMI) with left heart failure. After one hour infusion of dobutamine (mean dose: 6.3 micrograms/kg X min) there was an increase in cardiac index (27%, P less than 0.005), and a decrease in pulmonary wedge pressure (13%, P less than 0.025) and right atrial pressure (25%, P less than 0.025). The increase in oxygen delivery (23%, P less than 0.005) and mixed venous oxygen tension (10%, P less than 0.01) were neither accompanied by significant change in low arterial oxygen tension nor in high venous admixture. We conclude that dobutamine improves hemodynamics and oxygen delivery in AMI without affecting existant intrapulmonary shunting.
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
January 1980,
Journal of cardiovascular pharmacology,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
January 1979,
Acta medica Scandinavica,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
July 1981,
Circulation research,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
July 1984,
Kokyu to junkan. Respiration & circulation,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
July 1986,
Japanese circulation journal,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
March 1986,
Circulation,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
May 1986,
Ugeskrift for laeger,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
April 1977,
The American journal of cardiology,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
June 1986,
Kokyu to junkan. Respiration & circulation,
M Renard, and
P Jacobs, and
H Vainsel, and
R Bernard
April 1983,
Circulation,
