-transparent.png){kind=logo}
Synthetic bombesin was infused at a dose of 20 pmoles/kg/min for 10 min into the cranial pancreaticoduodenal artery of anesthetized dogs. Plasma immunoreactive glucagon concentrations in the cranial pancreaticoduodenal vein as well as in the femoral artery were concurrently and slowly elevated. However, the net release of glucagon from the pancreas did not increase significantly during infusion of bombesin. Plasma immunoreactive insulin concentrations in the pancreatic vein were transiently raised, and a delayed rise was noted in arterial plasma IRI. Net release of insulin was significantly augmented during infusion of the tetradecapeptide. Plasma glucose levels did not change after bombesin. These results indicate that the gastrointestinal tetradecapeptide may stimulate secretion of both insulin and gut glucagonlike immunoreactivity in the dog.
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
July 1977,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
September 1974,
Endocrinology,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
November 1975,
Endocrinology,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
September 1972,
Endocrinology,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
May 1971,
Endocrinology,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
April 1983,
The Journal of clinical endocrinology and metabolism,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
May 1970,
The New England journal of medicine,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
March 1982,
Regulatory peptides,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
December 1973,
Endocrinologia japonica,
A Kaneto, and
T Kaneko, and
S Nakaya, and
H Kajinuma, and
K Kosaka
June 1973,
Metabolism: clinical and experimental,
