BIOMAT Database Logo BIOMAT Database Logo

Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. VI. Midgestational adenohypophyseal sensitivity to thyrotrophin-releasing hormone. 1984

R C Thommes, and D J Williams, and J E Woods

The functional abilities of 9.5-, 10.5-, 11.5-, and 12.5-day-old chick embryos to respond to exogenous thyrotrophin-releasing hormone (TRH) were evaluated by means of changes in plasma total thyroxine (T4). T4 concentrations were determined 3.0, 6.0, 12.0, and 24.0 hr after TRH treatment. The data of the present investigation show that chick embryo adenohypophyseal sensitivity to exogenous TRH, as evidenced by changes in plasma T4 levels, increase during the 10.5- to 12.5-day incubation interval; however, the pattern and magnitude of plasma T4 response to administered TRH change markedly between Days 10.5 and 11.5 of development. This modification of the adenohypophyseal response pattern corresponds in embryonic time with the previously reported increases in immunocytochemically demonstrable TSH cells within the adenohypophysis(R. C. Thommes, J. B. Martens, W. E. Hopkins, D. A. Griesbach, D. J. Williams, M. J. Sorrentino, P. Wernke, and J. E. Woods, 1981, In 'Ninth International Symposium of Comparative Endocrinology"; R. C. Thommes, J. B. Martens, W. E. Hopkins, M. J. Sorrentino, J. C. Caliendo, and J. E. Woods, 1983, Gen. Comp. Endocrinol. 51, 434-443).

UI MeSH Term Description Entries
D007030 Hypothalamo-Hypophyseal System A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS. Hypothalamic Hypophyseal System,Hypothalamo-Pituitary-Adrenal Axis,Hypophyseal Portal System,Hypothalamic-Pituitary Unit,Hypothalamic Hypophyseal Systems,Hypothalamic Pituitary Unit,Hypothalamo Hypophyseal System,Hypothalamo Pituitary Adrenal Axis,Portal System, Hypophyseal
D010903 Pituitary Gland, Anterior The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION. Adenohypophysis,Anterior Lobe of Pituitary,Anterior Pituitary Gland,Lobus Anterior,Pars Distalis of Pituitary,Adenohypophyses,Anterior Pituitary Glands,Anterior, Lobus,Anteriors, Lobus,Lobus Anteriors,Pituitary Anterior Lobe,Pituitary Glands, Anterior,Pituitary Pars Distalis
D011863 Radioimmunoassay Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation. Radioimmunoassays
D002642 Chick Embryo The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching. Embryo, Chick,Chick Embryos,Embryos, Chick
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013961 Thyroid Gland A highly vascularized endocrine gland consisting of two lobes joined by a thin band of tissue with one lobe on each side of the TRACHEA. It secretes THYROID HORMONES from the follicular cells and CALCITONIN from the parafollicular cells thereby regulating METABOLISM and CALCIUM level in blood, respectively. Thyroid,Gland, Thyroid,Glands, Thyroid,Thyroid Glands,Thyroids
D013973 Thyrotropin-Releasing Hormone A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND. Protirelin,Thyroliberin,Abbott-38579,Antepan,Proterelin Tartrate,Proterelin Tartrate Hydrate,Protirelin Tartrate (1:1),Relefact TRH,Stimu-TSH,TRH Ferring,TRH Prem,Thypinone,Thyroliberin TRH Merck,Thyrotropin-Releasing Factor,Thyrotropin-Releasing Hormone Tartrate,Abbott 38579,Abbott38579,Hydrate, Proterelin Tartrate,Prem, TRH,Stimu TSH,StimuTSH,TRH, Relefact,Tartrate Hydrate, Proterelin,Thyrotropin Releasing Factor,Thyrotropin Releasing Hormone,Thyrotropin Releasing Hormone Tartrate
D013974 Thyroxine The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. L-Thyroxine,Levothyroxine,T4 Thyroid Hormone,3,5,3',5'-Tetraiodothyronine,Berlthyrox,Dexnon,Eferox,Eltroxin,Eltroxine,Euthyrox,Eutirox,L-3,5,3',5'-Tetraiodothyronine,L-Thyrox,L-Thyroxin Henning,L-Thyroxin beta,L-Thyroxine Roche,Levo-T,Levothroid,Levothyroid,Levothyroxin Deladande,Levothyroxin Delalande,Levothyroxine Sodium,Levoxine,Levoxyl,Lévothyrox,Novothyral,Novothyrox,O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine,O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine,Oroxine,Sodium Levothyroxine,Synthroid,Synthrox,Thevier,Thyrax,Thyroxin,Tiroidine,Tiroxina Leo,Unithroid,L Thyrox,L Thyroxin Henning,L Thyroxin beta,L Thyroxine,L Thyroxine Roche,Levo T,Thyroid Hormone, T4

Related Publications

R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the developing chick embryo. VII. Immunocytochemical demonstration of thyrotrophin-releasing hormone.
January 1985, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. I TRH and TSH sensitivity.
February 1978, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Ontogeny of hypothalamo-adenohypophyseal-gonadal (HAG) interrelationships in the chick embryo.
December 1984, The Journal of experimental zoology,
R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. III. Total T4 levels in the plasma of decapitated chick embryos with adenohypophyseal transplants.
October 1980, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. IV. Immunocytochemical demonstration of TSH in the hypophyseal pars distalis.
September 1983, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. V. The effects of thyroidectomy on T4 levels in blood plasma.
May 1984, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Hypothalamo-adenohypophyseal-thyroid interrelationships in the chick embryo. II. Effects of thiourea treatment on plasma total thyroxine levels and thyroidal 125I uptake.
February 1979, General and comparative endocrinology,
R C Thommes, and D J Williams, and J E Woods
Thyrotropic and peripheral activities of thyrotrophin and thyrotrophin-releasing hormone in the chick embryo and adult chicken.
March 1988, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
R C Thommes, and D J Williams, and J E Woods
Maturation of the hypothalamo-adenohypophyseal-gonadal (HAG) axes in the chick embryo.
January 1987, The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry,
R C Thommes, and D J Williams, and J E Woods
Thyrotrophin releasing hormone and thyroid function.
August 1973, The Journal of endocrinology,
Copied contents to your clipboard!