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The characteristics of immune responsiveness were studied in 455 children aged 2 months to 14 years with the generalized forms of meningococcal infection. In children of all age groups an increase in the titers of antibodies to meningococci was revealed; this increase started from day 4 of the disease, reached its maximum at the end of week 3 or the beginning of week 4 and correlated with the severity of the disease and the age of the patients. A drop in the IgG level in the course of the disease and a rise in the IgM level by the end of week 2 were observed. A decrease in the content of T-lymphocytes at the acute period of the disease and an increase in the number of B-lymphocytes, especially by the end of week 2 of the disease, were established.
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
March 1975,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
May 1988,
Vrachebnoe delo,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
January 1978,
Vestnik otorinolaringologii,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
October 1981,
Pediatriia,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
January 1987,
Pediatriia,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
September 1980,
Voprosy okhrany materinstva i detstva,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
January 1981,
Terapevticheskii arkhiv,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
January 1986,
Sovetskaia meditsina,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
April 1988,
Klinicheskaia meditsina,
N A Korzhueva, and
D I Rybalko, and
V P Naglenko, and
A P Zinchenko
January 1994,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
