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Having summarised recent studies of the biochemical and rheological nature of bronchial secretions, the authors envisage different types of drugs which modify bronchial secretions: mucolytic agents, drugs modifying local water equilibrium and mucoregulators. According to the modes of action of these drugs and the nature of the secretory disturbances, the authors propose new therapeutic schemes. The treatment of chronic bronchial hypersecretion should not necessarily aim to fluidify the secretions but should normalize their rheological properties in order to improve mucociliary transport. The various fluidifiers and regulators of bronchial secretions are in no way interchangeable and should only be used when appropriate.
J M Polu, and
E Puchelle, and
P Sadoul
April 1982,
Horumon to rinsho. Clinical endocrinology,
J M Polu, and
E Puchelle, and
P Sadoul
January 1982,
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J M Polu, and
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P Sadoul
March 1982,
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J M Polu, and
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January 1980,
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J M Polu, and
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December 1975,
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J M Polu, and
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P Sadoul
February 1982,
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J M Polu, and
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January 1974,
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J M Polu, and
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P Sadoul
February 1994,
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J M Polu, and
E Puchelle, and
P Sadoul
September 1996,
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J M Polu, and
E Puchelle, and
P Sadoul
February 1978,
Wiener klinische Wochenschrift,
