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The subnuclear distribution of 3H-oestradiol-receptor complexes was studied in uterine tissue of ovariectomized adult rats. Nuclei were sonically disrupted and 8 different subnuclear fractions were isolated by discontinuous sucrose density gradient centrifugation. 3H-Oestradiol-receptor complexes, measured by hydroxylapatite column chromatography, were localized in a light chromatin fraction as well as in a heavy chromatin fraction. Using the hydroxylapatite chromatography technique it was possible to demonstrate three classes of oestradiol-receptor complexes which differ in affinity for the chromatin. Oestradiol-receptor complexes with a high affinity for the chromatin were predominantly localized in the heavy chromatin fraction, whereas complexes with a lower affinity for their acceptor sites were present in the lighter chromatin fraction.
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
October 1981,
The Biochemical journal,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
October 1972,
FEBS letters,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
April 1999,
The Journal of comparative neurology,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
February 1977,
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
July 1968,
Biochemical and biophysical research communications,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
February 1973,
Acta endocrinologica,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
January 1987,
Folia medica Cracoviensia,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
November 1985,
The Journal of endocrinology,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
January 1987,
Biochemical and biophysical research communications,
W de Boer, and
J de Vries, and
E Mulder, and
H J van der Molen
June 1974,
Biochemical and biophysical research communications,
