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The authors' study of the viscosities of various concentrations of sodium hyaluronate, chondroitin sulfate, and methylcellulose revealed that sodium hyaluronate and methylcellulose are pseudoplastic fluids in contrast to chondroitin sulfate, which is a Newtonian fluid. Pseudoplastic fluids are ideal for maintaining the anterior chamber, since they are more viscous at rest. Intermediate viscosity preparations of these three agents used as a thin endothelial coating gave excellent protection from intraocular lens abrasion. A highly viscous agent, eg, sodium hyaluronate 1%, in a thin layer produced extensive endothelial cell damage because it transmitted excessive shear force to the endothelium. A highly viscous agent, sodium hyaluronate 1% in a thick layer produced a physical barrier to compression with little endothelial damage. A low-viscosity agent, balanced salt solution provided insufficient protection against intraocular lens abrasion.
M E Hammer, and
T G Burch
August 1983,
American journal of ophthalmology,
M E Hammer, and
T G Burch
March 1983,
American journal of ophthalmology,
M E Hammer, and
T G Burch
March 1989,
Annals of ophthalmology,
M E Hammer, and
T G Burch
January 1987,
Eye (London, England),
M E Hammer, and
T G Burch
November 1948,
The Journal of biological chemistry,
M E Hammer, and
T G Burch
July 1984,
Ophthalmology,
M E Hammer, and
T G Burch
January 2002,
International orthopaedics,
M E Hammer, and
T G Burch
January 2016,
Medical hypothesis, discovery & innovation ophthalmology journal,
M E Hammer, and
T G Burch
January 1977,
Society of General Physiologists series,
M E Hammer, and
T G Burch
February 1974,
Analytical biochemistry,
