Observations on the effects of CO2-laser on rat myocardium. 1984

E R Owen, and P Canfield, and K Bryant, and P R Hopwood

The effect of CO2-laser burn on rat myocardium was studied to evaluate a hypothesis developed by Mirhoseini and Cayton that infarcted myocardium may be revascularized by establishing an alternative circulation from a ventricle to the coronary arteries by means of laser channels burned through the myocardium. The hearts of 22 rats were examined histologically for a period ranging from a few minutes to 50 days after CO2 laser was applied to the myocardium. The laser initiated an intense inflammatory response in the myocardium adjacent to the target site. The authors believe that the inflammatory response, observed in this study to the Biophy-Las 80 surgical laser, must be reduced if laser is to be an effective means of myocardial revascularization.

UI MeSH Term Description Entries
D007249 Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. Innate Inflammatory Response,Inflammations,Inflammatory Response, Innate,Innate Inflammatory Responses
D007834 Lasers An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum. Masers,Continuous Wave Lasers,Pulsed Lasers,Q-Switched Lasers,Continuous Wave Laser,Laser,Laser, Continuous Wave,Laser, Pulsed,Laser, Q-Switched,Lasers, Continuous Wave,Lasers, Pulsed,Lasers, Q-Switched,Maser,Pulsed Laser,Q Switched Lasers,Q-Switched Laser
D008297 Male Males
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D005347 Fibroblasts Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules. Fibroblast
D006097 Granulation Tissue A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells. Granulation Tissues,Tissue, Granulation,Tissues, Granulation
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

E R Owen, and P Canfield, and K Bryant, and P R Hopwood
January 1991, Lasers in surgery and medicine,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
October 1995, Journal of dental research,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
January 2009, Journal of drugs in dermatology : JDD,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
November 1976, Journal of morphology,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
June 2004, International journal of pediatric otorhinolaryngology,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
April 1959, Bollettino della Societa italiana di biologia sperimentale,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
June 1987, Journal of periodontology,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
July 1973, Internationale Zeitschrift fur angewandte Physiologie, einschliesslich Arbeitsphysiologie,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
January 1974, Zeitschrift fur experimentelle Chirurgie,
E R Owen, and P Canfield, and K Bryant, and P R Hopwood
December 1988, Il Giornale di chirurgia,
Copied contents to your clipboard!