Biomaterial Database

Circulation and acid-base balance in exercising goats at different body temperatures. 1984

G Feistkorn, and A Nagel, and C Jessen

Thirty experiments were performed in two goats at an air temperature of +35 degrees C and a relative humidity of 33%. By means of heat exchangers, body core temperature (Tpaor) was adjusted to 39, 40.5, or 42 degrees C and maintained at these levels for 120 min. During the last 60 min the animals worked at a rate of 1.2 W/kg (treadmill, 3 km/h, 15%). Blood gases (arteriovenous O2 difference, Po2, Pco2), hemoglobin (Hb), blood lactate (LA), cardiac output (CO), blood pressure (MAP), heart rate (HR), metabolic rate (M), and respiratory evaporative heat loss (REHL) were determined. M, CO, HR, and Hb increased with exercise and were independent of Tpaor. At rest and exercise, REHL increased and Pco2 decreased at higher levels of Tpaor resulting in a respiratory alkalosis. During exercise this was accompanied by an increase in LA. At all instants, the concentrations of LA were higher at higher Tpaor. It is concluded that in a virtually nonsweating species like the goat the overall stress on the circulatory system caused by hyperthermia during exercise is relatively small while the behavior of blood LA is indicative of a temperature-dependent accumulation of LA also in the exercising muscle.

UI	MeSH Term	Description	Entries
D007773	Lactates	Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D010313	Partial Pressure	The pressure that would be exerted by one component of a mixture of gases if it were present alone in a container. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Partial Pressures,Pressure, Partial,Pressures, Partial
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D001775	Blood Circulation	The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM.	Blood Flow,Circulation, Blood,Blood Flows,Flow, Blood
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D001831	Body Temperature	The measure of the level of heat of a human or animal.	Organ Temperature,Body Temperatures,Organ Temperatures,Temperature, Body,Temperature, Organ,Temperatures, Body,Temperatures, Organ
D001833	Body Temperature Regulation	The processes of heating and cooling that an organism uses to control its temperature.	Heat Loss,Thermoregulation,Regulation, Body Temperature,Temperature Regulation, Body,Body Temperature Regulations,Heat Losses,Loss, Heat,Losses, Heat,Regulations, Body Temperature,Temperature Regulations, Body,Thermoregulations
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D002302	Cardiac Output	The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).	Cardiac Outputs,Output, Cardiac,Outputs, Cardiac