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The effects of long-term treatment with gliclazide on diabetic retinopathy and platelet adhesion were investigated. The subjects comprised 25 patients with NIDDM, of which 12 cases and 13 cases were treated with gliclazide and glibenclamide respectively. An improvement in retinopathy was observed in 7 out of 12 cases in the gliclazide-treated group. Of the remaining 5 cases, four cases remained unchanged and one deteriorated. Of the 13 cases treated with glibenclamide, on the other hand, only two cases showed an improvement in retinopathy after treatment, 7 cases remained unchanged and 4 cases deteriorated. The values for the platelet adhesion test following 3 years treatment were 52 +/- 14% and 42 +/- 17% in the gliclazide and the glibenclamide-treated groups respectively. These results were not statistically significant. These data indicate that gliclazide might be more effective than glibenclamide with respect to either improving diabetic retinopathy or preventing its progression.
N Minami, and
Y Ikeda, and
M Abe
January 1983,
Journees annuelles de diabetologie de l'Hotel-Dieu,
N Minami, and
Y Ikeda, and
M Abe
May 1982,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
N Minami, and
Y Ikeda, and
M Abe
January 1979,
Advances in experimental medicine and biology,
N Minami, and
Y Ikeda, and
M Abe
December 2005,
Diabetes research and clinical practice,
N Minami, and
Y Ikeda, and
M Abe
December 1983,
The Tohoku journal of experimental medicine,
N Minami, and
Y Ikeda, and
M Abe
January 1985,
Therapie,
N Minami, and
Y Ikeda, and
M Abe
June 2019,
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,
N Minami, and
Y Ikeda, and
M Abe
January 2006,
Journal of diabetes and its complications,
N Minami, and
Y Ikeda, and
M Abe
January 1990,
Acta diabetologica latina,
N Minami, and
Y Ikeda, and
M Abe
October 2020,
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association,
