-transparent.png){kind=logo}
Low levels of zinc in serum and high in blood clots were found in 12 patients with Down's syndrome (DS). They also had an immune deficiency characterized by depressed neutrophil chemotaxis, skin hypersensitivity and lymphocyte responsiveness to PHA in vitro. The patients received zinc sulphate, corresponding to 135 mg Zn++ daily. After treatment for 2 months' serum zinc levels had increased, neutrophil chemotactic responsiveness was normal in 11 of the 12 patients and there were improved lymphocyte responses to high doses of PHA in vitro. Delayed skin reactivity to DNCB was also improved in 10 of 11 patients after zinc therapy. Zinc deficiency may in part explain the increased susceptibility to infection in DS.
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
January 1982,
American journal of diseases of children (1960),
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
June 1994,
Annals of the New York Academy of Sciences,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
February 1989,
Minerva pediatrica,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
December 1978,
Journal of mental deficiency research,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
February 1986,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
August 1972,
Lancet (London, England),
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
March 1988,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
June 1970,
Journal of mental deficiency research,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
December 1993,
Journal of trace elements and electrolytes in health and disease,
B Björkstén, and
O Bäck, and
K H Gustavson, and
G Hallmans, and
B Hägglöf, and
A Tärnvik
June 1988,
Journal of mental deficiency research,
