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Primary cancer of gallbladder was detected by ultrasonography in 16 patients (10 women, 6 men), and confirmed at operation. Two main types of lesion were found: 8 localized forms (infiltrating or vegetating), and 8 diffuse forms with infiltration of the gallbladder wall. The lesion was an adenocarcinoma in each case, and there was associated lithiasis in 11 patients. Extension by contiguity or metastases is independent of the size of the cancer. Problems related to etiological and differential diagnosis of these lesions are discussed in relation to the different ultrasonography appearances observed.
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