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This study describes the mortality experience of a cohort of 61 males involved in a 1964 chloracne incident. Presumably as a result of skin absorption of the process contaminant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD or dioxin), 49 of these trichlorophenol production workers developed the skin condition. Within the limitations posed by cohort size and length of follow-up, TCDD does not appear to have adversely affected mortality experience. Overall, four deaths occurred and 7.8 were expected. Of these, one death was due to cardiovascular disease (3.8 expected) and three deaths were attributed to cancer (1.6 expected). None of the findings were statistically significant at alpha = 0.05. Further follow-up is contemplated.
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 2004,
Report on carcinogens : carcinogen profiles,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 2002,
Report on carcinogens : carcinogen profiles,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 1989,
Neurotoxicology and teratology,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 2006,
Reviews on environmental health,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 2012,
Frontiers in oncology,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
August 2013,
Environmental and molecular mutagenesis,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
October 1985,
Toxicology and applied pharmacology,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 1985,
International journal of immunopharmacology,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 1992,
Archives of environmental health,
R R Cook, and
J C Townsend, and
M G Ott, and
L G Silverstein
January 1991,
The New England journal of medicine,
