The human eyeblink, elicited by a tap to the glabella, can be inhibited if a relatively weak acoustic signal precedes the tap by approximately 100 msec. The work reported here was designed to explore the surprising fact that more inhibition occurs when the acoustic prestimulation is presented monaurally than when it is presented binaurally. The present studies revealed that (a) given equally loud binaural inputs, a reduction of about 40 dB(A) in one of them is sufficient to produce inhibition comparable to that produced by a monaural signal, (b) the difference between nonaural and binaural inhibition remains constant as the intensity of prestimulation is varied, and (c) the simultaneous offset of a tone in one ear and onset of a tone in the other ear produces more inhibition than either monaural offest or onset alone. These findings suggest that the specific attributes of a given acoustic signal make independent contributions to the inhibition produced by that signal.