-transparent.png){kind=logo}
The effects of oral and intravenous thyrotropin-releasing hormone (TRH) were studied in 11 male, chronic schizophrenic inpatients in an open trial and a double-blind, crossover design. The general beneficial effects of TRH as assessed on the Brief Psychiatric Rating Scale were not obtained, although improvement of contact, apathy and emotional rapport was observed in a few patients. Serum prolactin, L-triiodothyronine and thyroxine were assayed throughout the study. Since the effects of TRH on behavior were not related to changes in these endocrine factors, the mechanism of action might be independent of its original functions on the pituitary-thyroid axis.
Related Publications
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
January 1975,
Folia psychiatrica et neurologica japonica,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
January 1993,
Neuropsychobiology,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
November 1975,
Lancet (London, England),
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
November 1972,
Lancet (London, England),
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
January 1977,
Psychoneuroendocrinology,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
April 1974,
Nihon Jinzo Gakkai shi,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
March 1997,
Archives of general psychiatry,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
September 1995,
Journal of neurochemistry,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
August 1971,
Nordisk medicin,
K Kobayashi, and
K Nakaoka, and
H Tsuji, and
T Shohmori
January 1974,
Advances in internal medicine,
