A 14q+ chromosome in adult T-cell leukemia. 1981

K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi

Chromosome studies were conducted on two patients with adult T-cell leukemia. In both patients, a marker chromosome 14q+ and a structural change involving chromosome 1 with trisomy of the q arm were found in peripheral blood leukocytes. The 14q+ marker chromosome had resulted from translocation from #5p in one patient and #5q in the other patient. The present and previous studies suggest that the donor chromosomes involved in the 14q+ translocation are variable. This indicates that the 14q+ marker chromosome rather than the donor chromosome is intimately related with adult T-cell leukemia.

UI MeSH Term Description Entries
D007621 Karyotyping Mapping of the KARYOTYPE of a cell. Karyotype Analysis Methods,Analysis Method, Karyotype,Analysis Methods, Karyotype,Karyotype Analysis Method,Karyotypings,Method, Karyotype Analysis,Methods, Karyotype Analysis
D007938 Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) Leucocythaemia,Leucocythemia,Leucocythaemias,Leucocythemias,Leukemias
D007962 Leukocytes White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES). Blood Cells, White,Blood Corpuscles, White,White Blood Cells,White Blood Corpuscles,Blood Cell, White,Blood Corpuscle, White,Corpuscle, White Blood,Corpuscles, White Blood,Leukocyte,White Blood Cell,White Blood Corpuscle
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002900 Chromosomes, Human, 1-3 The large, metacentric human chromosomes, called group A in the human chromosome classification. This group consists of chromosome pairs 1, 2, and 3. Chromosomes A,Group A Chromosomes,Chromosome, Group A,Chromosomes, Group A,Group A Chromosome
D002901 Chromosomes, Human, 13-15 The medium-sized, acrocentric human chromosomes, called group D in the human chromosome classification. This group consists of chromosome pairs 13, 14, and 15. Chromosomes D,Group D Chromosomes,Chromosome, Group D,Chromosomes, Group D,Group D Chromosome
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013601 T-Lymphocytes Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. T Cell,T Lymphocyte,T-Cells,Thymus-Dependent Lymphocytes,Cell, T,Cells, T,Lymphocyte, T,Lymphocyte, Thymus-Dependent,Lymphocytes, T,Lymphocytes, Thymus-Dependent,T Cells,T Lymphocytes,T-Cell,T-Lymphocyte,Thymus Dependent Lymphocytes,Thymus-Dependent Lymphocyte

Related Publications

K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
September 1981, The New England journal of medicine,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
February 1996, The Journal of pathology,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
November 1986, [Rinsho ketsueki] The Japanese journal of clinical hematology,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
January 1994, Cancer research,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
January 1984, Medical and pediatric oncology,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
February 1979, Blood,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
November 1996, Cancer genetics and cytogenetics,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
August 1984, Journal of the National Cancer Institute,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
January 1981, Advances in cancer research,
K Miyamoto, and J Sato, and K Kitajima, and K Hamazaki, and T Adachi, and T Sato, and N Noda, and H Hioka, and H Sanada, and T Tanaka, and H Taguchi
January 1983, Acta haematologica,
Copied contents to your clipboard!