Biomaterial Database

The generation of aerosols of carcinogenic aromatic amines. 1978

S M Rappaport, and D J Gettemy

A system for producing test atmospheres of carcinogenic aromatic amines is discussed. The aerosol generator, a specially disigned compressed-gas nebulizer, operated at a temperature above each compound's melting point utlizing nitrogen as the driving force. The nebulizer output and size distributions of aerosols of 4,4'-methylenebis(2-chloroaniline) (MOCA), benzidine, and 3,3'-dichlorobenzidine are given.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D008753	Methylenebis(chloroaniline)	Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms.	Methylene Bis(chloroaniline),3,3'-Dichloro-4,4'-Diaminodiphenylmethane,4,4'-Methylenebis(2-chloroaniline),MBOCA
D010316	Particle Size	Relating to the size of solids.	Particle Sizes,Size, Particle,Sizes, Particle
D002273	Carcinogens	Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.	Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D000335	Aerosol Propellants	Compressed gases or vapors in a container which, upon release of pressure and expansion through a valve, carry another substance from the container. They are used for cosmetics, household cleaners, and so on. Examples are BUTANES; CARBON DIOXIDE; FLUOROCARBONS; NITROGEN; and PROPANE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Propellants, Aerosol
D000336	Aerosols	Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.	Aerosol
D001559	Benzhydryl Compounds	Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.	Diphenylmethyl Compounds,Compounds, Benzhydryl,Compounds, Diphenylmethyl
D001560	Benzidines	Very toxic industrial chemicals. They are absorbed through the skin, causing lethal blood, bladder, liver, and kidney damage and are potent, broad-spectrum carcinogens in most species.	Bianilines,Biphenyldiamines
D015101	3,3'-Dichlorobenzidine	A material used in the manufacture of azo dyes that is toxic to skin and carcinogenic in several species.	3,3-Dichlorobenzidine,3,3 Dichlorobenzidine,3,3' Dichlorobenzidine