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Penicillinase-producing Neisseria gonorrhoeae. 1981

R A Williams

Penicillinase-producing Neisseria gonorrhoeae (PPNG) causes the same clinical picture as nonpenicillinase-producing gonococci. Definitive identification depends on demonstration of penicillin resistance followed by tests for the beta-lactamase enzyme (penicillinase). Spectinomycin is the drug of choice but should be carefully reserved for laboratory-confirmed PPNG. Other drugs are effective. Over 2,000 cases have been reported since 1976, most originating in the Far East. Continuing spread is a certainty.

UI MeSH Term Description Entries
D007273 Injections, Intramuscular Forceful administration into a muscle of liquid medication, nutrient, or other fluid through a hollow needle piercing the muscle and any tissue covering it. Intramuscular Injections,Injection, Intramuscular,Intramuscular Injection
D008297 Male Males
D009344 Neisseria gonorrhoeae A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA. Diplococcus gonorrhoeae,Gonococcus,Gonococcus neisseri,Merismopedia gonorrhoeae,Micrococcus der gonorrhoe,Micrococcus gonococcus,Micrococcus gonorrhoeae
D010402 Penicillin G Procaine Semisynthetic antibiotic prepared by combining penicillin G with PROCAINE. Benzylpenicillin Procaine,Jenacillin,Procaine Penicillin,G Procaine, Penicillin,Penicillin, Procaine,Procaine, Benzylpenicillin,Procaine, Penicillin G
D010403 Penicillin Resistance Nonsusceptibility of an organism to the action of penicillins. Penicillin Resistances,Resistance, Penicillin,Resistances, Penicillin
D010405 Penicillinase A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-. beta-Lactamase I,AER-I beta-Lactamase,Benzylpenicillinase,Carbenicillinase,Exopenicillinase,beta Lactamase III,beta Lactamase RP4,gamma-Penicillinase,AER I beta Lactamase,Lactamase RP4, beta,beta Lactamase I,beta-Lactamase, AER-I,gamma Penicillinase
D010679 Philippines A country in southeastern Asia, archipelago between the Philippine Sea and the South China Sea, and east of Vietnam. The capital is Manila. Philipines,Phillipines,Phillippines
D011339 Probenecid The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. Benecid,Benemid,Benuryl,Pro-Cid,Probecid,Probenecid Weimer
D003140 Communicable Disease Control Programs of surveillance designed to prevent the transmission of disease by any means from person to person or from animal to man. Flatten the Curve of Epidemic,Flattening the Curve, Communicable Disease Control,Parasite Control,Control, Communicable Disease,Control, Parasite
D005260 Female Females

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