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Levels of carcinoembryonic antigen (CEA) activity were measured in 105 unselected samples of ascitic fluid submitted for routine cytologic analysis to ascertain whether this assay was useful in the detection of malignancy. The highest CEA level found in the 70 specimens of "benign" ascites was 10 ng/ml. Using values greater than 10 ng/ml as indicating a cancerous effusion, CEA assay successfully detected 14 of the 29 malignant ascites studied. Cytology, on the other hand, detected only 12 of these fluids. Combining the two methods increased the yield to 20. The CEA assay alone thus detected more than one fourth of these malignant fluids. The assay was particularly useful in detecting malignant transudates, nearly half of which had elevated CEA levels despite negative cytologic findings. The CEA assay of ascites thus showed promise as an adjunct to cytology in the detection of malignant ascites when used as part of a complete clinical and laboratory assessment.
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
December 1972,
National Cancer Institute monograph,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
January 1986,
Gastroenterologie clinique et biologique,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
December 2014,
Acta gastro-enterologica Belgica,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
September 1978,
Annals of internal medicine,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
April 1991,
Fortschritte der Medizin,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
February 1989,
The Indian journal of medical research,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
July 1973,
Cancer research,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
November 1974,
The Medical letter on drugs and therapeutics,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
March 1984,
Gastroenterologie clinique et biologique,
M S Loewenstein, and
R A Rittgers, and
A E Feinerman, and
H Z Kupchik, and
B R Marcel, and
R S Koff, and
N Zamcheck
March 1972,
Immunochemistry,
