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Stapedius reflex and brainstem auditory evoked responses in multiple sclerosis patients. 1984

R Grénman, and H Lang, and M Panelius, and A Salmivalli, and H Laine, and J Rintamäki

The stapedius reflex (SR), its adaptation and the brainstem auditory evoked potential (ABR) were recorded in a group of 53 multiple sclerosis patients. All cases were classified as definite according to Schumacher's criteria, and their grade of disability in Hyllested's system was 1-4: no cases of the gravest (grades 5 and 6) disability were included in the series. The peripheral hearing (pure-tone audiogram and speech threshold) was normal in 44 and slightly impaired in 8 cases. SR was abnormal in 6 (11%) and borderline in 11 (21%), whereas the ABR was considered abnormal in 21 (40%) patients. Deviant SR and ABR findings had only slight or no correlation to clinical data. Intercorrelation between SR and ABR abnormality was better but not implicit and a few cases with deviant ABR showed normal SR: The frequency of abnormal and borderline SR findings was clearly higher in bilateral than in unilateral ABR abnormality. Subclassification of ABR into an upper and a lower type of pathology did not correlate with SR abnormality.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009103 Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D012022 Reflex, Acoustic Intra-aural contraction of tensor tympani and stapedius in response to sound. Acoustic Reflex
D001933 Brain Stem The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA. Brainstem,Truncus Cerebri,Brain Stems,Brainstems,Cerebri, Truncus,Cerebrus, Truncus,Truncus Cerebrus
D005072 Evoked Potentials, Auditory The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS. Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001299 Audiometry The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds. Audiometries

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