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A 44-yr-old male presented with shortness of breath, diffuse X-ray infiltrates, and physiologic evidence of a restrictive lung disease. Biopsy revealed pulmonary alveolar proteinosis. The patient had worked for the previous 6 yr as an aluminum rail grinder in a very dusty environment. Analysis of his lung tissue revealed greater than 300 X 10(6) particles of aluminum/g dry lung; all of the particles appeared as spheres of less than 1 mu diameter. We believe that this case represents an example of pulmonary alveolar proteinosis induced by inhalation of aluminum particles; this finding confirms animal studies which suggest that proteinosis can be produced by very large doses of many types of finely divided mineral dust.
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
October 2009,
Lung India : official organ of Indian Chest Society,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
May 2007,
Occupational medicine (Oxford, England),
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
July 2016,
The Indian journal of chest diseases & allied sciences,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
March 1989,
Journal of occupational medicine. : official publication of the Industrial Medical Association,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
October 1998,
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
November 2013,
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
December 2013,
Respiratory investigation,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
November 2017,
BMC pulmonary medicine,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
June 2017,
American journal of industrial medicine,
R R Miller, and
A M Churg, and
M Hutcheon, and
S Lom
May 1997,
Pediatrics,
