-transparent.png){kind=logo}
The rare blood group phenotype lacking Lutheran antigens, Lu(a-b-), is known to have two genetic backgrounds. Tests on 250000 blood donors show the frequency of Lu(a-b-) to be approximately 1 in 3000. The families of 41 propositi show the dominant inhibitor of Lutheran antigens, In(Lu), to be the usual cause of the phenotype in South East England; there was no proven case of the recessive background, LuLu. Lod scores for In(Lu) and other blood group loci are presented; the only hint of linkage is between In(Lu) and Rh. The suppressing effect of In(Lu) on the expression of antigens of unrelated blood group systems, P1, Aua and i, is confirmed.
Related Publications
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
November 1957,
Blood,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
April 2014,
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
April 2019,
Transfusion medicine reviews,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
March 1974,
Vox sanguinis,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
January 1972,
Vox sanguinis,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
June 1997,
Blood,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
April 2013,
British journal of haematology,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
January 1977,
Transfusion,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
September 2008,
Blood,
M A Shaw, and
M R Leak, and
G L Daniels, and
P Tippett
January 1974,
Vox sanguinis,
