-transparent.png){kind=logo}
The fatty acid composition of platelet membranes has been analysed in patients with thrombocytosis due to myeloproliferative disorders, who had not taken any drugs. A significant increase in palmitic and oleic acid, together with a decrease in stearic, linoleic and arachidonic acids was observed. The fatty acid pattern of platelet membranes was also analysed in patients during treatment with ASA (acetylsalicylic acid). ASA ingestion completely normalizes the platelet content of palmitic acid and partially that of stearic and arachidonic acid, whereas it has no effect on the level of linoleic acid and raises that of oleic acid. The altered pattern of fatty acids observed in patients may interfere with platelet function by decreasing membrane fluidity. Treatment of patients with ASA seems to act on platelet membranes by partially normalizing the fatty acid composition.
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1981,
Haemostasis,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
June 1985,
British journal of haematology,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
October 2005,
Future oncology (London, England),
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
April 1986,
Scandinavian journal of clinical and laboratory investigation,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1982,
British journal of haematology,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1988,
Folia haematologica (Leipzig, Germany : 1928),
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1985,
Revista medica de Chile,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1992,
Haematologica,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
February 2008,
The European respiratory journal,
G Leoncini, and
M Maresca, and
F Balestrero, and
U Benatti, and
U Armani, and
A Piana
January 1987,
Cancer immunology, immunotherapy : CII,
