Biomaterial Database

High-performance liquid chromatography of corticosteroids in vertebrate plasma: assay of cortisol in mullet and corticosterone in the rat. 1984

P Thomas, and H W Wofford

Plasma corticosteroids of eighteen vertebrate species were separated by reversed-phase high-performance liquid chromatography (HPLC). The major corticosteroids identified in these species by HPLC agreed with previous reports which used vigorous criteria for identification. The HPLC technique was validated for the assay of cortisol in mullet plasma and corticosterone in the rat. Qualitative as well as quantitative changes in corticosteroid secretion were detected by HPLC in several vertebrates during exposure to stress.

UI	MeSH Term	Description	Entries
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D002025	Bufonidae	The family of true toads belonging to the order Anura. The genera include Bufo, Ansonia, Nectophrynoides, and Atelopus.	Bufo,Toads, True,Bufos,Toad, True,True Toad,True Toads
D002851	Chromatography, High Pressure Liquid	Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.	Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D003345	Corticosterone	An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
D005399	Fishes	A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006854	Hydrocortisone	The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.	Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D000305	Adrenal Cortex Hormones	HORMONES produced by the ADRENAL CORTEX, including both steroid and peptide hormones. The major hormones produced are HYDROCORTISONE and ALDOSTERONE.	Adrenal Cortex Hormone,Corticoid,Corticoids,Corticosteroid,Corticosteroids,Cortex Hormone, Adrenal,Hormone, Adrenal Cortex,Hormones, Adrenal Cortex
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

P Thomas, and H W Wofford

High-performance liquid chromatography and radioimmunoassay of rat plasma corticosterone.

May 1982, Steroids,

P Thomas, and H W Wofford

Analysis of corticosterone in rat plasma by high-performance liquid chromatography.

November 1994, Journal of chromatography. B, Biomedical applications,

P Thomas, and H W Wofford

High-performance liquid chromatography assay of amiodarone in rat plasma.

January 2001, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques,

P Thomas, and H W Wofford

Simultaneous assay of corticosterone and cortisol in plasma by reversed-phase liquid chromatography.

March 1992, Clinical chemistry,

P Thomas, and H W Wofford

Determination of plasma corticosterone using high-performance liquid chromatography.

August 1987, Journal of chromatography,

P Thomas, and H W Wofford

[Plasma assay of haloperidol by high performance liquid chromatography].

January 1985, Annales de biologie clinique,

P Thomas, and H W Wofford

Assay of gemfibrozil in plasma by "high-performance" liquid chromatography.

October 1987, Clinical chemistry,