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After hydrocortisone administration some properties of rat liver chromatin were studied by means of melting technique and circular dichroism. Hydrocortisone caused a more than 2.5-fold increase in amount of the chromatin active fraction. Distinct differences were detected between circular dichroism spectra of total chromatin and of its active fraction as well as between differential curves of the chromatin active fraction melting in control and test samples. The difference was expressed as a decrease in temperature of melting in a low-point zone and as appearance of the secondary maxima in the region of nucleosomes melting. These data suggest that the decondensation of nucleosome-containing sites takes place which is considered as an indirect evidence of the chromatin activation.
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
January 1987,
Ukrainskii biokhimicheskii zhurnal (1978),
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
February 1969,
Biochimica et biophysica acta,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
January 1985,
Ukrainskii biokhimicheskii zhurnal (1978),
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
October 1983,
Arkhiv anatomii, gistologii i embriologii,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
May 1987,
Biokhimiia (Moscow, Russia),
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
March 1981,
The Biochemical journal,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
November 1965,
Proceedings of the National Academy of Sciences of the United States of America,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
January 1987,
Molekuliarnaia biologiia,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
May 1972,
Ceskoslovenska farmacie,
A O Vardevanian, and
K S Matinian, and
R R Vardapetian, and
E S Gevorkian, and
G A Panosian
April 1966,
Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete,
