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Sera from 84 uremic patients (53 on conservative treatment and 31 on hemodialysis) were studied spectrofluorometrically in comparison with 20 normal subjects and 11 jaundiced patients. Serum fluorescence in patients with chronic renal failure was significantly higher than in normals and patients with jaundice. Two types of serum fluorescence spectra (A and B) were predominant (93%) and all the patients who were free of any medication for more than two months exhibited the type A spectrum. The intensity of fluorescence was in parallel with the serum creatinine levels. Dialysis experiments of uremic serum in vitro showed that the substance(s) responsible for its fluorescence is dialyzable. Moreover hemodialysis caused a significant decrease in the intensity of serum fluorescence in dialyzed patients. Administration of pyridoxine intravenously caused quite different results in normal subjects and uremic patients. Namely normals presented a transient (for several minutes) increase in serum fluorescence whereas uremics showed a higher and more permanent increase which lasted for several days.
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
December 1980,
Gut,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
July 1979,
Acta endocrinologica,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
September 1987,
Kidney international,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
December 1983,
Kidney international. Supplement,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
November 1983,
The International journal of artificial organs,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
January 1994,
Przeglad lekarski,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
January 1995,
Nephron,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
May 2000,
Journal of the American Society of Nephrology : JASN,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
April 1980,
Clinical chemistry,
A G Hadjivassiliou, and
G E Digenis, and
D Mayopoulou-Symvoulidis, and
S Voudiclari, and
N Tsaparas, and
A Symvoulidis
January 1974,
Gynecologic investigation,
