-transparent.png){kind=logo}
Alterations in ornithine decarboxylase (ODC) activity and in the polyamine and nucleic acid (RNA and DNA) concentrations were studied in P388 leukemia cells and in the host liver at different times after intraperitoneal inoculation of 5 X 10(6) tumor cells into BDF1 mice. ODC activity of leukemia cells had a maximum at day 5 after tumor transplantation. Cellular spermidine concentration declined significantly during the first 5 to 6 days. The RNA concentration of tumor cells changed parallel to that of spermidine. In the livers of ascites tumor-bearing mice ODC activity was 5- to 20-fold of control and had a maximum at days 5 to 6 after tumor cell inoculation. Spermidine concentration in the host liver increased, whereas spermine decreased gradually with tumor growth.
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1989,
Anticancer research,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
October 1973,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1981,
Journal of immunopharmacology,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1985,
Anticancer research,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1972,
Journal of the National Cancer Institute,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1983,
Cancer drug delivery,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1993,
Anticancer research,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1988,
Experimental cell biology,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
May 1974,
International journal of cancer,
T Kremmer, and
L Selmeci, and
S Bardócz, and
L Holczinger, and
S Bálint
January 1982,
Cellular and molecular biology,
