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It has been demonstrated in a long-term experiment that the corneal endothelium of the rabbit is capable of repairing severe mechanical lesions several times. The more severe the lesion, the longer it takes to heal. The endothelium "broke down" for the first time after the sixth endothelial lesion was inflicted and so on after the tenth, eleventh and twelfth endothelial lesion. The regeneration time was prolonged considerably. Sometimes a "restitutio ad integrum" occurs and the cornea clarifies; sometimes one sees a retrocorneal membrane, which can also lead to clarification of the cornea. Plastic platelets implanted in addition (PVAL or HEMA copolymers) do not influence the time required for regeneration of the endothelium. In other tests these plastics proved to be nontoxic to the endothelium.
W Ehrich, and
H Höh
March 1975,
Archives d'ophtalmologie et revue generale d'ophtalmologie,
W Ehrich, and
H Höh
January 1986,
Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft,
W Ehrich, and
H Höh
January 1983,
Nippon Ganka Gakkai zasshi,
W Ehrich, and
H Höh
January 1981,
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology,
W Ehrich, and
H Höh
February 1984,
Nippon Ganka Gakkai zasshi,
W Ehrich, and
H Höh
December 1961,
Archives of ophthalmology (Chicago, Ill. : 1960),
W Ehrich, and
H Höh
February 1975,
Experimental eye research,
