Biomaterial Database

Eimeria acervulina infection and the zinc-cadmium interrelationship in the chick. 1984

K W Bafundo, and D H Baker, and P R Fitzgerald

The purpose of this study was to evaluate the effects of Eimeria acervulina infection (duodenal coccidiosis) on cadmium (Cd) toxicity and zinc (Zn) status in the young chick. Additions of Cd (45 mg/kg) were made to diets that contained either 0 or 52 mg/kg supplemental Zn (from ZnCO3). Duodenal coccidiosis was produced by multiple crop inoculations of 4 X 10(5) sporulated E. acervulina oocysts. Growth and efficiency of feed utilization were reduced by dietary Cd addition while concurrent coccidial infection reduced these parameters further. Addition of Cd also increased Cd content of liver and kidney and depressed hemoglobin, hematocrit, and plasma Zn content. Coccidial infection exacerbated tissue Cd deposition and depressed hematological parameters further. Although dietary Zn addition ameliorated some of the adverse effects of Cd toxicity, Cd administration tended to enhance tissue Zn deposition. Administration of Cd enhanced synthesis of metallothionein.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D011201	Poultry Diseases	Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.	Disease, Poultry,Diseases, Poultry,Poultry Disease
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D002104	Cadmium	An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D002254	Carbonates	Salts or ions of the theoretical carbonic acid, containing the radical CO2(3-). Carbonates are readily decomposed by acids. The carbonates of the alkali metals are water-soluble; all others are insoluble. (From Grant & Hackh's Chemical Dictionary, 5th ed)	Carbonate
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D003048	Coccidiosis	Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA.	Besnoitiasis,Besnoitiosis,Besnoitiases,Besnoitioses,Coccidioses
D004347	Drug Interactions	The action of a drug that may affect the activity, metabolism, or toxicity of another drug.	Drug Interaction,Interaction, Drug,Interactions, Drug
D004378	Duodenal Diseases	Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).	Disease, Duodenal,Diseases, Duodenal,Duodenal Disease
D004539	Eimeria	A genus of protozoan parasites of the subclass COCCIDIA. Various species are parasitic in the epithelial cells of the liver and intestines of man and other animals.	Eimerias