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In 161 children with ages ranging from 7 months to 18 years the concentration of CK-BB in serum was measurable in 58%. The activity in serum of CK-BB (cCK-BB(S] in children varies with age and is not significantly influenced by seizure, epilepsy or body temperature. The values are most elevated during the first year of life and show a rapid fall, never reaching adult levels. Comparing mean cCK-BB(S) values in children to growth charts the resemblance is striking. CK-BB is the only CK-isoenzyme that changes with age. We postulate that cCK-BB(S) is related to growth as a physiological phenomenon. CK-MB was found in serum in 7% of the children and could not be of cardiac origin. Therefore CK-MB cannot be regarded as cardiac specific in children.
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
January 1989,
La Tunisie medicale,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
March 1983,
Clinical chemistry,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
January 1986,
Zeitschrift fur medizinische Laboratoriumsdiagnostik,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
January 1991,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
January 1982,
Annals of clinical and laboratory science,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
November 1982,
Clinical chemistry,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
March 1978,
Clinical chemistry,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
May 1998,
Journal of cell science,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
July 1978,
Klinische Wochenschrift,
F B Jørgensen, and
J Badskjaer, and
B S Pedersen, and
K Boysen
August 1977,
Clinica chimica acta; international journal of clinical chemistry,
