At first some problems of topic terms are demonstrated because the method is transferred from rodents and cattle. Therefore we should not term it a biotechnical but a biomedical approach involving the specific human and ethic aims. The eF and ET method is described and characterized as a systemic one which makes possible to improve the chances of numerous infertile couples and to elucidate some problems of early embryonic development. In spite of the tendency to standardize and to alleviate the method there is no reason to estimate it easy. In 1983 our three GDR groups performed 20 ET's over all but without an ongoing pregnancy until now.